For women with postmenopausal osteoporosis at high risk for fracture

Bone Remodeling, Osteoporosis and Your Bones

For most of our lives, our bones go through a remodeling process. This means that our bodies are constantly breaking down old bone and forming new, healthy bone.

How osteoporosis happens in women after menopause

The bone remodeling process

For women, estrogen helps regulate the bone remodeling process. However, estrogen levels decline after menopause. This causes women to lose bone more quickly. This imbalance in the bone remodeling process can lead to osteoporosis — even in active postmenopausal women in their 50s.

Illustration of osteoclast cell

Bone resorption

Osteoclasts break down and remove old bone (resorption).

Illustration of osteoblast cell

Bone formation

Osteoblasts form new bone to replace the bone lost through resorption.

Illustration of the bone remodeling process and how osteoclasts break down and remove old bone, and osteoblasts build new bone.

Understanding bone density

Bone mineral density (BMD) is the amount of bone mineral in your bones. When your bones are less dense, they are more fragile. Women with osteoporosis generally have low bone density.

The inside of bones is made up of a matrix or latticework of material that looks like a sponge.

Use the slider to see the difference between healthy bone and osteoporotic bone

Healthy
Bone

As you can see, healthy bone is porous on the inside.

OSTEOPOROTIC
Bone

In osteoporotic bone there is even more open space, and the bone is fragile.

Slider icon is pulled to the left showing more osteoporotic bone. The description says that in osteoporotic bone there is even more open space, and the bone is fragile.
Slider is pulled to the right showing more healthy bone. The description says that healthy bone is porous on the inside.

Understanding T-scores

When your doctor measures your BMD you will get a T-score, which compares your BMD with the average BMD of young adults.

Here are some examples of bones with different BMD T-scores

Healthy bone

HEALTHY BONE

T-score: -1 and above

Osteopenic bone

OSTEOPENIC BONE

T-score: -2.5 to -1

Osteoporotic bone

BONE WITH OSTEOPOROSIS

T-score: less than -2.5

If you've had a fracture of the spine or a fragility fracture (due to a fall from standing height or less), you may be diagnosed with osteoporosis, regardless of T-scores. Be sure to tell your healthcare team if you've had a recent fracture, particularly if it was caused by a simple fall or movement.

Orange check mark in a circle icon

Don't forget

Ask your doctor how postmenopausal osteoporosis can affect the quality of your bones.

We know you're

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Purple glow Woman stands with her arm flexed. The bones on her side are highlighted bright purple.

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