For women with postmenopausal osteoporosis at high risk for fracture

The more you know, the more you can do

For most of our lives, our bones go through a remodeling process. This means that our bodies are constantly breaking down old bone and forming new, healthy bone.

How osteoporosis happens in women after menopause

The bone remodeling process

For women, estrogen helps regulate the bone remodeling process. However, estrogen levels decline after menopause. This causes women to lose bone more quickly. This imbalance in the bone remodeling process can lead to osteoporosis — even in active postmenopausal women in their 50s.

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Bone resorption

Osteoclasts break down and remove old bone (resorption).

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Bone formation

Osteoblasts form new bone to replace the bone lost through resorption.

Understanding bone density

Bone mineral density (BMD) is the amount of bone mineral in your bones. When your bones are less dense, they are more fragile. Women with osteoporosis generally have low bone density.

The inside of bones is made up of a matrix or latticework of material that looks like a sponge.

Use the slider to see the difference between healthy bone and osteoporotic bone

Healthy
Bone

As you can see, healthy bone is porous on the inside.

OSTEOPOROTIC
Bone

In osteoporotic bone there is even more open space, and the bone is fragile.

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Understanding T-scores

When your doctor measures your BMD you will get a T-score, which compares your BMD with the average BMD of young adults.

Here are some examples of bones with different BMD T-scores

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HEALTHY BONE

T-score: -1 and above

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OSTEOPENIC BONE

T-score: -2.5 to -1

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BONE WITH OSTEOPOROSIS

T-score: less than -2.5

If you’ve had a fracture of the spine or fragility fracture, you may be diagnosed with osteoporosis, regardless of T-score.

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Don't forget

Be sure to keep up with your bone density scans, and tell all of your physicians if you've broken a bone from a simple fall or movement.

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What is the most important information I should know about TYMLOS?

TYMLOS may cause serious side effects including: Possible bone cancer (osteosarcoma). During animal drug testing, TYMLOS caused some rats to develop a bone cancer called osteosarcoma. It is not known if people who take TYMLOS will have a higher chance of getting osteosarcoma. READ MORE